Semeraro Francesco, Morescalchi Francesco, Duse Sarah, Gambicorti Elena, Russo Andrea, Costagliola Ciro
Department of Medical and Surgical Specialties, Radiological Specialties and Public Health, Ophthalmology Clinic, University of Brescia, 25123 Brescia, Italy.
Department of Medicine and Health Sciences, University of Molise, 86100 Campobasso, Italy ; I.R.C.C.S. Neuromed, Località Camerelle, Pozzilli, 86077 Isernia, Italy.
J Ophthalmol. 2015;2015:671905. doi: 10.1155/2015/671905. Epub 2015 Sep 3.
The inner limiting membrane (ILM) is the basement membrane of the Müller cells and can act as a scaffold for cellular proliferation in the pathophysiology of disorders affecting the vitreomacular interface. The atraumatic removal of the macular ILM has been proposed for treating various forms of tractional maculopathy in particular for macular pucker. In the last decade, the removal of ILM has become a routine practice in the surgery of the epiretinal membranes (ERMs), with good anatomical results. However many recent studies showed that ILM peeling is a procedure that can cause immediate traumatic effects and progressive modification on the underlying inner retinal layers. Moreover, it is unclear whether ILM peeling is helpful to improve vision after surgery for ERM. In this review, we describe the current understanding about ILM peeling and highlight the beneficial and adverse effects associated with this surgical procedure.
内界膜（ILM）是 Müller 细胞的基底膜，在影响玻璃体黄斑界面的疾病病理生理学中，可作为细胞增殖的支架。已提出无创性去除黄斑 ILM 用于治疗各种形式的牵引性黄斑病变，尤其是黄斑皱襞。在过去十年中，去除 ILM 已成为视网膜前膜（ERM）手术中的常规操作，取得了良好的解剖学效果。然而，最近许多研究表明，ILM 剥除术是一种会对下方的视网膜内层造成即刻创伤效应和渐进性改变的手术。此外，尚不清楚 ILM 剥除术是否有助于改善 ERM 手术后的视力。在本综述中，我们描述了目前对 ILM 剥除术的认识，并强调了与该手术相关的有益和不良影响。
