Liss P, Nygren A, Revsbech N P, Ulfendahl H R
Department of Diagnostic Radiology, University Hospital, Uppsala, Sweden.
Adv Exp Med Biol. 1997;411:569-76. doi: 10.1007/978-1-4615-5865-1_70.
The oxygen tension (PO2) in the rat kidney was studied by modified Clark microelectrodes. Changes in PO2 were measured in the renal cortex and outer medulla after intravenous injections of the X-ray contrast medium (CM) diatrizoate, 370 mg iodine/mg body weight. Injection of diatrizoate caused a slight fall in PO2 in the renal cortex (from 42 +/- 4 to 38 +/- 4 mm Hg). In the medulla PO2 decreased significantly (from 34 +/- 6 to 20 +/- 4 mm Hg). Ringer's solution did not induce any changes.
采用改良的克拉克微电极研究了大鼠肾脏中的氧分压(PO2)。静脉注射X射线造影剂(CM)泛影葡胺(370毫克碘/毫克体重)后,测量了肾皮质和外髓质中PO2的变化。注射泛影葡胺导致肾皮质中的PO2略有下降(从42±4降至38±4毫米汞柱)。在外髓质中,PO2显著降低(从34±6降至20±4毫米汞柱)。林格氏液未引起任何变化。