Wedell J, Schmutzler W, Kayser D
Langenbecks Arch Chir. 1977 Nov 4;344(2):131-40. doi: 10.1007/BF01259387.
The experimental occlusion of the superior mesenteric artery in dogs is followed by a significant rise of serotonin-, kinin- and katecholamin-concentrations in the portal vein blood. The rise of the prostaglandin-F2alpha-concentration occurred only immediately after the occlusion or reopening of the occluded superior mesenteric artery. Under our experimental conditions the measured concentrations of these substances in the portal vein blood are too low and ineffective for the development of peptic erosions in the stomach as observed after occlusion of the superior mesenteric artery. On the other hand a possible additiv effect of the underswelling concentrations in these different substances cannot be excluded.
对狗的肠系膜上动脉进行实验性闭塞后,门静脉血中血清素、激肽和儿茶酚胺的浓度显著升高。仅在肠系膜上动脉闭塞或重新开放后立即出现前列腺素-F2α浓度升高。在我们的实验条件下,门静脉血中这些物质的测量浓度过低,对肠系膜上动脉闭塞后观察到的胃消化性溃疡的发生无效。另一方面,不能排除这些不同物质中低浓度的可能叠加作用。