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[肠系膜上动脉闭塞后犬门静脉血中药理活性物质的显示(作者译)]

[The demonstration of pharmacological active substances in the portal vein blood of dogs after occlusion of the superior mesenteric artery (author's transl)].

作者信息

Wedell J, Schmutzler W, Kayser D

出版信息

Langenbecks Arch Chir. 1977 Nov 4;344(2):131-40. doi: 10.1007/BF01259387.

DOI:10.1007/BF01259387
PMID:926958
Abstract

The experimental occlusion of the superior mesenteric artery in dogs is followed by a significant rise of serotonin-, kinin- and katecholamin-concentrations in the portal vein blood. The rise of the prostaglandin-F2alpha-concentration occurred only immediately after the occlusion or reopening of the occluded superior mesenteric artery. Under our experimental conditions the measured concentrations of these substances in the portal vein blood are too low and ineffective for the development of peptic erosions in the stomach as observed after occlusion of the superior mesenteric artery. On the other hand a possible additiv effect of the underswelling concentrations in these different substances cannot be excluded.

摘要

对狗的肠系膜上动脉进行实验性闭塞后,门静脉血中血清素、激肽和儿茶酚胺的浓度显著升高。仅在肠系膜上动脉闭塞或重新开放后立即出现前列腺素-F2α浓度升高。在我们的实验条件下,门静脉血中这些物质的测量浓度过低,对肠系膜上动脉闭塞后观察到的胃消化性溃疡的发生无效。另一方面,不能排除这些不同物质中低浓度的可能叠加作用。

相似文献

1
[The demonstration of pharmacological active substances in the portal vein blood of dogs after occlusion of the superior mesenteric artery (author's transl)].[肠系膜上动脉闭塞后犬门静脉血中药理活性物质的显示(作者译)]
Langenbecks Arch Chir. 1977 Nov 4;344(2):131-40. doi: 10.1007/BF01259387.
2
Serotonin levels in portal vein plasma after occlusion of the superior mesenteric artery in dogs with intact and divided vagus nerves.
Surgery. 1973 Sep;74(3):333-7.
3
The effect of high cervical cordotomy on portal vein plasma serotonin and 5-hydroxyindoleacetic acid levels in dogs with and without superior mesenteric artery occlusion.高位颈髓切断术对伴有和不伴有肠系膜上动脉闭塞的犬门静脉血浆5-羟色胺和5-羟吲哚乙酸水平的影响。
Surgery. 1975 Jan;77(1):154-9.
4
Role of pancreatic blood flow and vasoactive substances in the development of canine acute pancreatitis.胰腺血流和血管活性物质在犬急性胰腺炎发展中的作用。
J Surg Res. 1993 Nov;55(5):531-6. doi: 10.1006/jsre.1993.1179.
5
[Change in the activity of the histamine and serotonin systems in acute obstruction of the mesenteric vessels].[肠系膜血管急性阻塞时组胺和5-羟色胺系统活性的变化]
Biull Eksp Biol Med. 1980 Feb;89(2):153-5.
6
[Experimental occlusion of the superior mesenteric artery: further evidence of the influence of histamine and diamine oxidase in the development of shock (author's transl)].[实验性肠系膜上动脉闭塞:组胺和二胺氧化酶在休克发生发展中作用的进一步证据(作者译)]
Chir Forum Exp Klin Forsch. 1980:267-70.
7
The lung lesion produced by materials released from the superior mesenteric vein after superior mesenteric arterial occlusion.
Jpn Circ J. 1971 Sep;35(9):1071-80. doi: 10.1253/jcj.35.1071.
8
[Studies of shock produced by superior mesenteric artery occlusion--changes of adrenocortical hormones (author's abstract)].[肠系膜上动脉闭塞所致休克的研究——肾上腺皮质激素的变化(作者摘要)]
Masui. 1978 Apr;27(4):343-8.
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The effect of haemorrhage on gastric circulation and acid output in the dog.出血对犬胃循环及胃酸分泌的影响。
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10
[Thrombosis of the portal and superior mesenteric veins in a patient with a congenital and familial deficiency in antithrombin III (author's transl)].抗凝血酶III先天性家族性缺乏患者的门静脉和肠系膜上静脉血栓形成(作者译)
Ann Med Interne (Paris). 1979;130(2):53-7.

本文引用的文献

1
An Experimental Production of Coronary Thrombosis and Myocardial Failure.冠状动脉血栓形成与心肌衰竭的实验性产生
Can Med Assoc J. 1936 Jan;34(1):9-15.
2
Relation of anemia and hemorrhagic shock to experimental ulcer production.贫血和失血性休克与实验性溃疡形成的关系。
Proc Soc Exp Biol Med. 1948 May;68(1):125-8. doi: 10.3181/00379727-68-16412.
3
Hemodynamics of the stomach. II. Relation between gastric secretion and blood flow.胃的血流动力学。II. 胃液分泌与血流之间的关系。
Am J Dig Dis. 1962 Sep;7:786-90. doi: 10.1007/BF02231911.
4
A method for the fluorometric assay of histamine in tissues.一种用于组织中组胺荧光测定的方法。
J Pharmacol Exp Ther. 1959 Nov;127:182-6.
5
A STUDY OF THE FACTORS INVOLVED IN THE DEVELOPMENT OF PERIPHERAL VASCULAR COLLAPSE FOLLOWING RELEASE OF THE OCCLUDED SUPERIOR MESENTERIC ARTERY.
Br J Surg. 1965 Sep;52:699-704. doi: 10.1002/bjs.1800520917.
6
EXPERIMENTALLY INDUCED VARIATIONS IN CANINE GASTRIC BLOOD FLOW AND ITS DISTRIBUTION.犬胃血流及其分布的实验性诱导变化。
Am J Physiol. 1965 Feb;208:353-8. doi: 10.1152/ajplegacy.1965.208.2.353.
7
THE CIRCULATION OF THE STOMACH.胃的血液循环
Gastroenterology. 1965 Jan;48:85-109.
8
CIRCULATING SEROTONIN AND CATECHOLAMINES FOLLOWING OCCLUSION OF THE SUPERIOR MESENTERIC ARTERY.肠系膜上动脉闭塞后的循环血清素和儿茶酚胺
Ann Surg. 1964 Dec;160(6):1062-5. doi: 10.1097/00000658-196412000-00020.
9
A STUDY OF GASTRIC SECRETION AND BLOOD FLOW IN THE ANAESTHETIZED DOG.麻醉犬胃分泌与血流的研究
J Physiol. 1963 Aug;168(1):219-33. doi: 10.1113/jphysiol.1963.sp007188.
10
Hypothalamic influence on gastric, mesenteric blood flow.下丘脑对胃、肠系膜血流的影响。
Surg Forum. 1962;13:280-2.