Merzhanova G Kh, Dolbakian E E, Partev A Z
Zh Vyssh Nerv Deiat Im I P Pavlova. 1997 May-Jun;47(3):500-6.
The alimentary instrumental conditioned bar-pressing reflex was elaborated in cats by the method of "active choice" of either short-delayed reinforcement with bread-meat mixture of delayed more valuable reinforcement with meat. The animals differed in behavior strategy: some animals preferred bar-pressing with the long delay (the so-called "self-control" group), other animals pressed the bar with short delay (the so-called "impulsive" group). The multiunit activity in the basolateral amygdala was recorded with chronically implanted nichrome microelectrodes. The interactions between the spike trains of the neighbouring neurons selected from the multiunit activity were evaluated by means of statistical crosscorrelation analysis. It was shown that the number of correlations between the discharges of neurons was significantly higher in the "impulsive" cats. In both groups the number of cross-correlations was maximal in cases of a difficult choice, i.e., during the omission of the conditioned bar-pressing response. In "impulsive" cats the number of interneuronal correlations was highest with the latencies in the range of 0-30 msec. We suggest that the basolateral amygdala is involved in the system of structures which determine the individual-typological characteristics of animals.
通过“主动选择”的方法，在猫身上建立了消化道工具性条件性压杆反射，即选择用面包 - 肉混合物进行短延迟强化，或者选择用肉进行延迟时间更长的更有价值的强化。动物在行为策略上存在差异：一些动物更喜欢长延迟压杆（所谓的“自我控制”组），另一些动物则短延迟压杆（所谓的“冲动”组）。用长期植入的镍铬微电极记录基底外侧杏仁核中的多单位活动。通过统计互相关分析评估从多单位活动中选取的相邻神经元的脉冲序列之间的相互作用。结果表明，“冲动”型猫的神经元放电之间的相关性数量显著更高。在两组中，在困难选择的情况下，即条件性压杆反应被省略时，互相关的数量最大。在“冲动”型猫中，神经元间相关性数量在潜伏期为0 - 30毫秒范围内最高。我们认为基底外侧杏仁核参与了决定动物个体类型特征的结构系统。
