Breddin K, Krzywanek H J
Prog Biochem Pharmacol. 1977;13:339-43.
In clinical investigation on ehnanced platelet aggregation the changes of the various tests with time after blood sampling must be considered. The photometric PAT III for the evaluation of spontaneous aggregation showed enhanced aggregation in a high percentage of patients with vascular disease, and prospective data obtained so far make it likely that enhanced aggregation is a risk factor for thrombosis. More prospective studies are necessary to prove whether continuously enhanced spontaneous platelet aggregation is indicating progressive atherosclerosis.
在关于血小板聚集增强的临床研究中，必须考虑采血后各项检测结果随时间的变化。用于评估自发聚集的光度法PAT III显示，在高比例的血管疾病患者中存在聚集增强现象，而且目前获得的前瞻性数据表明，聚集增强可能是血栓形成的一个危险因素。需要更多的前瞻性研究来证明持续增强的自发血小板聚集是否预示着动脉粥样硬化的进展。
