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记忆缺陷与工业毒物暴露:硬质合金、溶剂和石棉工人的比较研究

Memory deficits and industrial toxicant exposure: a comparative study of hard metal, solvent and asbestos workers.

作者信息

Jordan C M, Whitman R D, Harbut M

机构信息

University of Minnesota Health Center, USA.

出版信息

Int J Neurosci. 1997 Jun;90(1-2):113-28. doi: 10.3109/00207459709000631.

Abstract

Memory functioning was examined in ex-factory workers with hard metal disease, resulting from exposure to alloys utilizing cobalt. Since these workers are also exposed to organic solvents and may suffer from chronic hypoxia as a result of their pulmonary disorder, solvent and asbestos workers, as well as an unexposed matched sample, served as controls. Results demonstrated deficits in the allocation of attentional resources and in short-term verbal memory. A pattern of findings across several tests suggested that repetition or delay is important for adequate memory performance in individuals exposed to hard metal, implicating a deficit in encoding or slowed consolidation.

摘要

对患有硬金属病的前工厂工人的记忆功能进行了检查,这些工人因接触含钴合金而患病。由于这些工人还接触有机溶剂,并且可能因其肺部疾病而患有慢性缺氧,因此溶剂工人、石棉工人以及未接触过有害物质的匹配样本作为对照。结果表明,在注意力资源分配和短期言语记忆方面存在缺陷。多项测试的结果模式表明,重复或延迟对于接触硬金属的个体的充分记忆表现很重要,这意味着编码缺陷或巩固过程减慢。

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