Tos M, Charabi S, Thomsen J
Department of ORL, Head and Neck Surgery, Gentofte University Hospital, Hellerup, Denmark.
Acta Otolaryngol Suppl. 1997;529:53-5. doi: 10.3109/00016489709124079.
The incidence of acoustic neuroma/vestibular schwannoma (VS) in Denmark, with a population of approximately 5 million inhabitants was estimated in 3 periods: June 1976-June 1983, July 1983-June 1990 and July 1990-December 1995. The incidence of tumors increased from 7.8 tumors per million per year in the first period to 9.5 tumors per million per year in the second period. The figure of 12 tumors per million per year is established in the third period. A significant increase of the newly diagnosed intracanalicular and small tumors, with an extracanalicular extension of 1-10 mm was observed in the third period compared with the first 2 periods. Correspondingly a decrease in the newly diagnosed giant tumors was noted in the last 2 periods compared with the first period.
在丹麦,约有500万居民,对听神经瘤/前庭神经鞘瘤(VS)的发病率在三个时间段进行了估算:1976年6月至1983年6月、1983年7月至1990年6月以及1990年7月至1995年12月。肿瘤发病率从第一个时间段的每年每百万7.8例肿瘤增加到第二个时间段的每年每百万9.5例肿瘤。在第三个时间段确定为每年每百万12例肿瘤。与前两个时间段相比,在第三个时间段观察到新诊断的管内型和小型肿瘤(伴有1 - 10毫米的管外扩展)显著增加。相应地,与第一个时间段相比,在后两个时间段注意到新诊断的巨大肿瘤有所减少。