Rosen Carol
Divisions of Epidemiology, Neurology, Pulmonology, Department of Pediatrics, Case Western Reserve University-University Hospitals Health System, Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Sleep Breath. 2000;4(4):177-182. doi: 10.1007/s11325-000-0177-8.
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common sleep disorder in adults that is increasingly recognized in children, affecting 1 to 3% of children. Children experience a spectrum of severity related to the degree of upper airway obstruction, the duration of the disease, and the presence or absence of hypoxemic episodes. Failure to diagnose and treat OSAHS can result in serious, but generally reversible consequences for the child including impaired growth, neurocognitive and behavioral dysfunction, and cardiorespiratory failure. Even mild OSAHS appears linked to reversible health consequences. Adenotonsillar hypertrophy is the major predisposing factor for OSAHS in childhood. However, enlarged tonsils and adenoids can be a normal finding in young children and are not diagnostic for OSAHS. The identification of children with OSAHS is often difficult because affected children may have no signs or symptoms when awake. Furthermore, clinical assessment cannot reliably distinguish between simple snoring and OSAHS. Adenotonsillectomy is the most common therapy for OSAHS in children, but surprisingly, only a small percentage of children undergo any diagnostic testing prior to surgery. Thus, the challenge is to develop new diagnostic strategies that effectively screen, identify, and treat children most likely to benefit from specific treatment.
阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是成人常见的睡眠障碍,目前在儿童中也越来越受到关注,约1%至3%的儿童受其影响。儿童OSAHS的严重程度因上气道阻塞程度、疾病持续时间以及是否存在低氧血症发作而异。未能诊断和治疗OSAHS会给儿童带来严重但通常可逆的后果,包括生长发育受损、神经认知和行为功能障碍以及心肺功能衰竭。即使是轻度OSAHS似乎也与可逆的健康后果有关。腺样体扁桃体肥大是儿童OSAHS的主要诱发因素。然而,扁桃体和腺样体肿大在幼儿中可能是正常现象,并非OSAHS的诊断依据。识别OSAHS患儿往往很困难,因为患病儿童在清醒时可能没有任何体征或症状。此外,临床评估无法可靠地区分单纯打鼾和OSAHS。腺样体扁桃体切除术是儿童OSAHS最常见的治疗方法,但令人惊讶的是,只有一小部分儿童在手术前接受任何诊断测试。因此,挑战在于开发新的诊断策略,以有效地筛查、识别和治疗最有可能从特定治疗中受益的儿童。