Koh W Y, Lew T W, Chin N M, Wong M F
Department of Anaesthesia and Intensive Care, Tan Tock Seng Hospital, Singapore.
Anaesth Intensive Care. 1997 Aug;25(4):365-8. doi: 10.1177/0310057X9702500407.
A retrospective review was made of 49 survivors who were mechanically ventilated for more than 48 hours in the neurosurgical ICU. Thirty-two patients (Gp I) were successfully extubated, 9 patients (Gp II) underwent tracheostomy after one or more failed extubations, and 8 patients (Gp III) underwent elective tracheostomy. Glasgow Coma Scale (GCS) scores at extubation were 11.3 +/- 2.8 (mean (SD) for Gp I vs 7.8 +/- 2.7 for Gp II (P = n.s.) and at elective tracheostomy (Gp III) was 5.4 +/- 2.3. Incidence of ventilator-associated pneumonia were 35% in Gp I vs 100% of patients in Gp II and III (P < 0.05). Reasons for reintubation in 7 of 9 patients (Gp II) were upper airway obstruction and tenacious tracheal secretions while 14 of 17 patients were weaned off the ventilator within 48 hours of tracheostomy. The length of stay in ICU was 16.8 +/- 7.1 days in Gp II vs 11.7 +/- 2.9 days in Gp III (P < 0.05). In our study, elective tracheostomy for selected patients with poor GCS scores and nosocomial pneumonia has resulted in shortened ICU length of stay and rapid weaning from ventilatory support.
对49名在神经外科重症监护病房接受机械通气超过48小时的幸存者进行了回顾性研究。32名患者(第一组)成功拔管,9名患者(第二组)在一次或多次拔管失败后进行了气管切开术,8名患者(第三组)进行了选择性气管切开术。拔管时格拉斯哥昏迷量表(GCS)评分,第一组为11.3±2.8(均值(标准差)),第二组为7.8±2.7(P值无统计学意义),选择性气管切开术时(第三组)为5.4±2.3。第一组呼吸机相关性肺炎的发生率为35%,第二组和第三组患者为100%(P<0.05)。9名患者(第二组)中有7名再次插管的原因是上呼吸道梗阻和气管分泌物黏稠,而17名患者中有14名在气管切开术后48小时内脱机。第二组在重症监护病房的住院时间为16.8±7.1天,第三组为11.7±2.9天(P<0.05)。在我们的研究中,对格拉斯哥昏迷量表评分低且患有医院获得性肺炎的特定患者进行选择性气管切开术,缩短了重症监护病房的住院时间,并使患者迅速脱离通气支持。