糖尿病和高血压的新药与临床试验。

New drugs and clinical trials in diabetes and hypertension.

作者信息

Nilsson P

机构信息

Department of Community Health Sciences, University of Lund, Sweden.

出版信息

Exp Clin Endocrinol Diabetes. 1997;105 Suppl 2:64-9. doi: 10.1055/s-0029-1211801.

DOI:10.1055/s-0029-1211801

PMID:9288549

Abstract

Hypertension is a well-established risk factor for cerebro-cardiovascular disease in diabetics, as well as for progressing renal disease. Several pathophysiological mechanisms link hypertension with non-insulin-dependent diabetes (NIDDM), e.g. insulin resistance. This will be discussed below as regards pathophysiology and treatment possibilities, especially with new drugs in ongoing clinical trials.

摘要

高血压是糖尿病患者发生心脑血管疾病以及肾病进展的一个公认的危险因素。有几种病理生理机制将高血压与非胰岛素依赖型糖尿病（NIDDM）联系起来，例如胰岛素抵抗。以下将从病理生理学和治疗可能性方面进行讨论，特别是正在进行临床试验的新药。