Lee C S, Chu I M
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan, Republic of China.
Artif Organs. 1997 Sep;21(9):1002-6.
Various modifications of alginate-poly-L-lysine microcapsules were made, such as the inclusion of polyethylenimine (PEI) or carboxyl methyl cellulose (CMC) in the core and the coating of bis(polyoxyethylene bis[amine]) (PEGA) onto the microcapsule membrane surface. A characterization of the modified microcapsules in terms of mechanical and mass transfer properties as well as their chemical composition was performed. The PEI treatment greatly enhanced the mechanical stability of the microcapsules, and this treatment did not affect the coating process of poly-L-lysine or PEGA. PEGA was found to be able to coat the microcapsules while the mass transfer property was similar to the poly-L-lysine coated ones.
对海藻酸钠-聚-L-赖氨酸微胶囊进行了各种改性，例如在核心中加入聚乙烯亚胺（PEI）或羧甲基纤维素（CMC），并在微胶囊膜表面包覆双（聚氧乙烯双[胺]）（PEGA）。对改性微胶囊的机械性能、传质性能及其化学成分进行了表征。PEI处理大大提高了微胶囊的机械稳定性，且该处理不影响聚-L-赖氨酸或PEGA的包覆过程。发现PEGA能够包覆微胶囊，同时其传质性能与聚-L-赖氨酸包覆的微胶囊相似。
