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[一种诊断雷诺现象的有用方法:手指缺血后反应性充血的冷抑制]

[A useful method for the diagnosis of Raynaud's phenomenon: cold suppression of reactive post-ischemic hyperemia in the fingers].

作者信息

Krähenbühl B

出版信息

Schweiz Med Wochenschr. 1977 Dec 10;107(49):1831-3.

PMID:929146
Abstract

A method is described which is of assistance in diagnosing Raynaud's phenomenon by making it possible to estimate the degree of cold sensitivity. 5-minute ischemia provoked by tourniquet round the wrist results in reactive finger hyperemia when the tourniquet is released. In 25 of 28 patients with Raynaud's phenomenon, postischemia reactive hyperemia was suppressed by cooling the hand to between 10 and 20 degrees, but remained unchanged in normal subjects. The critical temperature at which Raynaud's phenomenon occurs can be determined in a given patient, and the natural history of the disease and the effect of treatment can be observed. Cold induced reactive hyperemia suppression is probably caused by Burton's critical closing phenomenon.

摘要

本文描述了一种有助于诊断雷诺现象的方法,该方法能够评估冷敏感性程度。用止血带环绕手腕造成5分钟的局部缺血,松开止血带后会出现手指反应性充血。28例雷诺现象患者中有25例,将手部冷却至10至20度时,缺血后反应性充血受到抑制,但正常受试者的反应性充血保持不变。可以确定特定患者发生雷诺现象的临界温度,并且能够观察疾病的自然病程和治疗效果。冷诱导的反应性充血抑制可能是由伯顿临界闭合现象引起的。

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