Melikyan G B, Chernomordik L V
Dept of Molecular Biophysics and Physiology, Rush Medical College, Chicago, IL 60612, USA.
Trends Microbiol. 1997 Sep;5(9):349-55. doi: 10.1016/S0966-842X(97)01107-4.
Diverse enveloped viruses enter host cells by fusing their envelopes with cell membranes. The mechanisms of merger of lipid bilayers of two membranes mediated by influenza hemagglutinin and other viral fusion proteins apparently involve local lipidic connections that evolve into a bilayer septum in which a pore forms and expands.
多种包膜病毒通过将其包膜与细胞膜融合进入宿主细胞。由流感血凝素和其他病毒融合蛋白介导的两个膜的脂质双层融合机制显然涉及局部脂质连接，这些连接演变成一个双层隔膜，在其中形成并扩大一个孔。
