探究宿主细胞内的细菌基因表达。
Probing bacterial gene expression within host cells.
作者信息
Valdivia R H, Falkow S
机构信息
Dept of Microbiology and Immunology, Stanford University School of Medicine, CA 94305, USA.
出版信息
Trends Microbiol. 1997 Sep;5(9):360-3. doi: 10.1016/S0966-842X(97)01111-6.
PMID:9294892
Abstract
The study of bacterial gene expression in the host environment is critical to our understanding of the disease process. New research tools, such as luciferase and green fluorescent protein, provide the means to measure bacterial responses to the intracellular environment with minimal perturbations and with single-cell resolution.
摘要
研究宿主环境中的细菌基因表达对于我们理解疾病过程至关重要。新的研究工具，如荧光素酶和绿色荧光蛋白，提供了以最小干扰和单细胞分辨率来测量细菌对细胞内环境反应的方法。
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