Bahramali H, Gordon E, Lim C L, Li W, Lagopoulos J, Leslie J, Rennie C, Meares R A
Department of Psychological Medicine, Westmead Hospital and The University of Sydney, NSW, Australia.
Neuroreport. 1997 Aug 18;8(12):2665-9. doi: 10.1097/00001756-199708180-00006.
Late component event related potentials (ERP) and concomitant electrodermal activity (EDA) measures of the orienting reflex (OR) were undertaken in 50 normal subjects. Our group recently developed a model to quantify electrodermal activity in conventional ERP paradigms (auditory oddball) with short interstimulus intervals (ISI). The method was used to classify the presence or absence of skin conductance response following each auditory target stimulus. Using a conventional paradigm in which data is traditionally averaged, single-trial target ERPs were sorted into those with a skin conductance response OR (ERP[+OR]) and those without (ERP[-OR]) an OR, and ERP sub-averages of the two groups were derived. The ERP(+OR) showed significantly larger P300 amplitudes and relatively earlier N200 and P300 latency than those of the ERP(-OR). These findings suggest that using concomitant SCR-ERP measures, separate ERP related processes can be determined, that are complementary to the traditional average measure.
对50名正常受试者进行了晚期成分事件相关电位（ERP）以及伴随的皮肤电活动（EDA）对定向反射（OR）的测量。我们的团队最近开发了一个模型，用于在具有短刺激间隔（ISI）的传统ERP范式（听觉Oddball范式）中量化皮肤电活动。该方法用于对每个听觉目标刺激后皮肤电导反应的有无进行分类。使用传统的将数据进行平均的范式，将单次试验的目标ERP分为具有皮肤电导反应OR的（ERP[+OR]）和没有OR的（ERP[-OR]），并得出两组的ERP子平均值。ERP(+OR)组的P300波幅明显大于ERP(-OR)组，且N200和P300潜伏期相对更早。这些发现表明，使用伴随的SCR-ERP测量方法，可以确定与ERP相关的不同过程，这些过程是对传统平均测量方法的补充。
