Crea F, Biasucci L M, Buffon A, Liuzzo G, Monaco C, Caligiuri G, Kol A, Sperti G, Cianflone D, Maseri A
Istituto di Cardiologia, Universita' Cattolica del Sacro Cuore, Rome, Italy.
Am J Cardiol. 1997 Sep 4;80(5A):10E-16E. doi: 10.1016/s0002-9149(97)00483-9.
In this article, the clinical, angiographic, and postmortem features of unstable angina are reviewed and its pathogenesis is discussed. Coronary plaque inflammation may play a key role in the pathogenesis of unstable angina and the evidence for this assertion is examined. Finally, the therapeutic implications of the involvement of inflammation in acute coronary syndromes are outlined.
本文回顾了不稳定型心绞痛的临床、血管造影及尸检特征,并探讨了其发病机制。冠状动脉斑块炎症可能在不稳定型心绞痛的发病机制中起关键作用,本文对此论断的证据进行了审视。最后,概述了炎症参与急性冠脉综合征的治疗意义。