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患有肝脏疾病的犬类肾血管阻力增加。

Increased renal vascular resistance in dogs with hepatic disease.

作者信息

Novellas Rosa, de Gopegui Rafael Ruiz, Espada Yvonne

机构信息

Animal Medicine and Surgery Department, Veterinary Teaching Hospital, Autonomous University of Barcelona, Spain.

出版信息

Vet J. 2008 Nov;178(2):257-62. doi: 10.1016/j.tvjl.2007.07.026. Epub 2007 Sep 12.

DOI:10.1016/j.tvjl.2007.07.026
PMID:17855130
Abstract

Doppler ultrasound is a non-invasive technique that can be used to estimate vascular resistance by calculation of resistive index (RI) and pulsatility index (PI). Liver disease may increase renal RI and PI, and in humans with liver disease the indices are monitored to attain prognostic information. Systemic hypertension has been found in dogs with hepatic disease and is also related to increased renal vascular resistance in humans. The aim of this study was to examine renal vascular resistance increases in dogs with hepatic disease and to ascertain whether these may be related to blood pressure increases and biochemical parameters. Twenty dogs with hepatic disease were evaluated. The mean renal RI, PI, and systolic blood pressure were significantly higher than in normal animals. A positive correlation was found between the indices and alkaline phosphatase but not with systolic blood pressure. It is concluded that renal vascular resistance may increase in dogs with hepatic disease and in this study was above the limit value in 50% of the animals.

摘要

多普勒超声是一种非侵入性技术,可通过计算阻力指数(RI)和搏动指数(PI)来估计血管阻力。肝脏疾病可能会增加肾RI和PI,在患有肝脏疾病的人类中,会监测这些指数以获取预后信息。在患有肝脏疾病的犬类中发现了系统性高血压,这也与人类肾血管阻力增加有关。本研究的目的是检查患有肝脏疾病的犬类肾血管阻力的增加情况,并确定这些增加是否与血压升高和生化参数有关。对20只患有肝脏疾病的犬进行了评估。平均肾RI、PI和收缩压显著高于正常动物。这些指数与碱性磷酸酶之间存在正相关,但与收缩压无关。得出的结论是,患有肝脏疾病的犬类肾血管阻力可能会增加,在本研究中,50%的动物肾血管阻力高于极限值。

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