• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

酿酒酵母表型综述。

A review of phenotypes in Saccharomyces cerevisiae.

作者信息

Hampsey M

机构信息

Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway 08854, USA.

出版信息

Yeast. 1997 Sep 30;13(12):1099-133. doi: 10.1002/(SICI)1097-0061(19970930)13:12<1099::AID-YEA177>3.0.CO;2-7.

DOI:10.1002/(SICI)1097-0061(19970930)13:12<1099::AID-YEA177>3.0.CO;2-7
PMID:9301019
Abstract

A summary of previously defined phenotypes in the yeast Saccharomyces cerevisiae is presented. The purpose of this review is to provide a compendium of phenotypes that can be readily screened to identify pleiotropic phenotypes associated with primary or suppressor mutations. Many of these phenotypes provide a convenient alternative to the primary phenotype for following a gene, or as a marker for cloning a gene by genetic complementation. In many cases a particular phenotype or set of phenotypes can suggest a function for the product of the mutated gene.

摘要

本文总结了酿酒酵母中先前定义的表型。本综述的目的是提供一份表型纲要,这些表型可以很容易地进行筛选,以识别与原发性或抑制性突变相关的多效性表型。其中许多表型为追踪基因提供了一种方便的替代主要表型的方法,或者作为通过遗传互补克隆基因的标记。在许多情况下,特定的一种或一组表型可以提示突变基因产物的功能。

相似文献

1
A review of phenotypes in Saccharomyces cerevisiae.酿酒酵母表型综述。
Yeast. 1997 Sep 30;13(12):1099-133. doi: 10.1002/(SICI)1097-0061(19970930)13:12<1099::AID-YEA177>3.0.CO;2-7.
2
[Genetic control of growth and development of yeast Saccharomyces cerevisiae cells. Phenotypic selection of mutants among strains of the Peterhof genetic collection].[酿酒酵母细胞生长与发育的遗传控制。彼得霍夫遗传库菌株中突变体的表型筛选]
Genetika. 2001 Jun;37(6):762-9.
3
[Genetic analysis of pleiotropic effects of pho85 mutations in yeast Saccharomyces cerevisiae].[酿酒酵母中pho85突变多效性效应的遗传分析]
Genetika. 2003 Aug;39(8):1039-45.
4
The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes.锚定去除技术:酵母突变体表型的快速、条件性建立。
Mol Cell. 2008 Sep 26;31(6):925-32. doi: 10.1016/j.molcel.2008.07.020.
5
Identification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae.酿酒酵母中G1-S转换期细胞周期阻滞的多拷贝抑制子的鉴定。
Yeast. 2003 Jan 30;20(2):157-69. doi: 10.1002/yea.938.
6
HIR1, the co-repressor of histone gene transcription of Saccharomyces cerevisiae, acts as a multicopy suppressor of the apoptotic phenotypes of the LSM4 mRNA degradation mutant.HIR1是酿酒酵母组蛋白基因转录的共抑制因子,作为LSM4 mRNA降解突变体凋亡表型的多拷贝抑制因子发挥作用。
FEMS Yeast Res. 2005 Dec;5(12):1229-35. doi: 10.1016/j.femsyr.2005.07.007. Epub 2005 Sep 6.
7
PGK1, the gene encoding the glycolitic enzyme phosphoglycerate kinase, acts as a multicopy suppressor of apoptotic phenotypes in S. cerevisiae.PGK1基因编码糖酵解酶磷酸甘油酸激酶,它在酿酒酵母中作为凋亡表型的多拷贝抑制因子发挥作用。
Yeast. 2009 Jan;26(1):31-7. doi: 10.1002/yea.1647.
8
Effects of aneuploidy on cellular physiology and cell division in haploid yeast.非整倍体对单倍体酵母细胞生理和细胞分裂的影响。
Science. 2007 Aug 17;317(5840):916-24. doi: 10.1126/science.1142210.
9
Epistatic participation of REV1 and REV3 in the formation of UV-induced frameshift mutations in cell cycle-arrested yeast cells.REV1和REV3在细胞周期停滞的酵母细胞中紫外线诱导的移码突变形成中的上位性参与。
Mutat Res. 2006 Jan 29;593(1-2):187-95. doi: 10.1016/j.mrfmmm.2005.07.012. Epub 2005 Sep 8.
10
Disruption of a gene encoding phosphatidic acid phosphatase causes abnormal phenotypes in cell growth and abnormal cytokinesis in Saccharomyces cerevisiae.编码磷脂酸磷酸酶的基因的破坏会导致酿酒酵母细胞生长中的异常表型和异常胞质分裂。
Biochem Biophys Res Commun. 1998 Jul 9;248(1):87-92. doi: 10.1006/bbrc.1998.8914.

引用本文的文献

1
Formation of giant ER sheets by pentadecanoic acid causes lipotoxicity in fission yeast.十五烷酸导致裂殖酵母形成巨大内质网片层从而引发脂毒性。
Proc Natl Acad Sci U S A. 2025 Jun 3;122(22):e2422126122. doi: 10.1073/pnas.2422126122. Epub 2025 May 27.
2
CURE on yeast genes of unknown function increases students' bioinformatics proficiency and research confidence.对未知功能酵母基因的CURE提高了学生的生物信息学能力和研究信心。
J Microbiol Biol Educ. 2024 Apr 25;25(1):e0016523. doi: 10.1128/jmbe.00165-23. Epub 2024 Jan 31.
3
Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III.
突变和生物物理分析揭示了 RNA 聚合酶 III 的 TFIIF 相关 Rpc53 亚基中的 TFIIIC 结合区域。
J Biol Chem. 2023 Jul;299(7):104859. doi: 10.1016/j.jbc.2023.104859. Epub 2023 May 23.
4
Yeast Chromatin Mutants Reveal Altered mtDNA Copy Number and Impaired Mitochondrial Membrane Potential.酵母染色质突变体揭示线粒体DNA拷贝数改变及线粒体膜电位受损。
J Fungi (Basel). 2023 Mar 7;9(3):329. doi: 10.3390/jof9030329.
5
Easy efficient HDR-based targeted knock-in in genome using CRISPR-Cas9 system.利用 CRISPR-Cas9 系统在基因组中进行简便高效的 HDR 靶向基因敲入。
Bioengineered. 2022 Jun;13(6):14857-14871. doi: 10.1080/21655979.2022.2162667.
6
Coevolution of the Ess1-CTD axis in polar fungi suggests a role for phase separation in cold tolerance.极地真菌中Ess1-CTD轴的共同进化表明相分离在耐寒性中发挥作用。
Sci Adv. 2022 Sep 9;8(36):eabq3235. doi: 10.1126/sciadv.abq3235. Epub 2022 Sep 7.
7
Marine natural products targeting the eukaryotic cell membrane.靶向真核细胞膜的海洋天然产物。
J Antibiot (Tokyo). 2021 Nov;74(11):769-785. doi: 10.1038/s41429-021-00468-5. Epub 2021 Sep 7.
8
Isolation of Indigenous Selenium Tolerant Yeast and Investigation of the Relationship Between Growth and Selenium Biotransformation.本土耐硒酵母的分离及生长与硒生物转化关系的研究
Adv Pharm Bull. 2020 Jan;10(1):146-149. doi: 10.15171/apb.2020.020. Epub 2019 Dec 11.
9
SCRaMbLE generates evolved yeasts with increased alkali tolerance.SCRaMbLE 可产生耐碱能力增强的进化酵母。
Microb Cell Fact. 2019 Mar 11;18(1):52. doi: 10.1186/s12934-019-1102-4.
10
In vitro assembly and proteomic analysis of RNA polymerase II complexes.体外组装和 RNA 聚合酶 II 复合物的蛋白质组学分析。
Methods. 2019 Apr 15;159-160:96-104. doi: 10.1016/j.ymeth.2019.03.001. Epub 2019 Mar 4.