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酿酒酵母表型综述。

A review of phenotypes in Saccharomyces cerevisiae.

作者信息

Hampsey M

机构信息

Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway 08854, USA.

出版信息

Yeast. 1997 Sep 30;13(12):1099-133. doi: 10.1002/(SICI)1097-0061(19970930)13:12<1099::AID-YEA177>3.0.CO;2-7.

Abstract

A summary of previously defined phenotypes in the yeast Saccharomyces cerevisiae is presented. The purpose of this review is to provide a compendium of phenotypes that can be readily screened to identify pleiotropic phenotypes associated with primary or suppressor mutations. Many of these phenotypes provide a convenient alternative to the primary phenotype for following a gene, or as a marker for cloning a gene by genetic complementation. In many cases a particular phenotype or set of phenotypes can suggest a function for the product of the mutated gene.

摘要

本文总结了酿酒酵母中先前定义的表型。本综述的目的是提供一份表型纲要,这些表型可以很容易地进行筛选,以识别与原发性或抑制性突变相关的多效性表型。其中许多表型为追踪基因提供了一种方便的替代主要表型的方法,或者作为通过遗传互补克隆基因的标记。在许多情况下,特定的一种或一组表型可以提示突变基因产物的功能。

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