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[ABO血型系统中亚组检测的误差]

[Errors in detection of subgroups in the ABO blood group system].

作者信息

Sato C, Maeda H

机构信息

Saitama Medical School, Blood Transfusion Service.

出版信息

Nihon Rinsho. 1997 Sep;55(9):2362-8.

PMID:9301301
Abstract

In the ABO blood group system, several subgroups have been described based on: 1) the difference of reactivities of the red cells with anti-A, anti-B, anti-A1, and anti-H, 2) the presence or absence of anti-A, anti-B, anti-A1, anti-H, and anti-HI in serum, and 3) the presence of A, B, H substances in the saliva of ABH secretors. Subgroups of A are more frequent in Caucasians than in Japanese, while those of B are more frequent in Japanese. Both the red cell typing (testing red cells for A and B antigens) and serum typing (testing the antibodies in the serum against red cells of known ABO groups) are important to identify and not to overlook these ABO subgroups. When transfusion is required in individuals with these subgroups, compatible blood products must be selected according to the presence or absence of antibodies active at 37 degrees C.

摘要

在ABO血型系统中,已根据以下几点描述了几个亚组:1)红细胞与抗A、抗B、抗A1和抗H的反应性差异;2)血清中抗A、抗B、抗A1、抗H和抗HI的有无;3)ABH分泌型者唾液中A、B、H物质的存在情况。A亚组在白种人中比在日本人中更常见,而B亚组在日本人中更常见。红细胞分型(检测红细胞上的A和B抗原)和血清分型(检测血清中针对已知ABO血型红细胞的抗体)对于识别和不忽视这些ABO亚组都很重要。当这些亚组的个体需要输血时,必须根据37℃时活性抗体的有无选择相容的血液制品。

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