Moreira C J, Perlowagora-Szumlewicz A
Nucleo de Biologia de Vetores e de Interação Vetor/Parasito, Rio de Janeiro, Brasil.
Mem Inst Oswaldo Cruz. 1997 Jan-Feb;92(1):91-6. doi: 10.1590/s0074-02761997000100019.
From June 1984 to July 1992, 392 xenodiagnostic tests were applied on 264 patients with chronic Chagas disease from Brazilian endemic areas of Virgem da Lapa and Coronel Murta, situated in the Jequitinhonha Valley, in the State of Minas Gerais. The susceptibilities of Rhodnius neglectus, Panstrongylus megistus, Triatoma vitticeps and Triatoma infestans were compared. Most of the time 20 nymphs (fourth instar) of each species were applied to 161 women and 103 men aged between 5 and 83 years of age. The tests were prepared to compare the susceptibilities of two species at a time, using the same patients for each test. Results showed a xenopositiveness of 26.28% (103 tests) being 27.98% in women (68 positive in 243 applied tests) and 23.49% in men (35 positive in 149 applied tests). The relative frequency of xenopositiveness displayed a great superiority of P. megistus and T. vitticeps. In tests from type 1, for example, P. megistus was the unique responsible for 10.73% of positive xenodiagnosis vs only 0.98% in T. infestans. Other parameters analized in this work confirm this superiority, and corroborate that T. infestans can be replaced by P. megistus and/or T. vitticeps in order to upgrade the efficacy of xenodiagnosis.
1984年6月至1992年7月，对来自米纳斯吉拉斯州热基蒂尼奥尼亚河谷的维尔京达拉萨和科罗内尔穆尔塔巴西地方病流行区的264例慢性恰加斯病患者进行了392次动物接种诊断试验。比较了忽视罗蝽、巨蝽、饰边锥蝽和骚扰锥蝽的易感性。大多数情况下，将每种20只若虫（四龄）应用于161名女性和103名年龄在5至83岁之间的男性。每次试验准备比较两个物种的易感性，每次试验使用相同的患者。结果显示动物接种阳性率为26.28%（103次试验），女性为27.98%（243次应用试验中有68次阳性），男性为23.49%（149次应用试验中有35次阳性）。动物接种阳性的相对频率显示巨蝽和饰边锥蝽具有极大优势。例如，在1型试验中，巨蝽是导致10.73%的动物接种诊断阳性的唯一原因，而骚扰锥蝽仅为0.98%。这项工作中分析的其他参数证实了这种优势，并证实为了提高动物接种诊断的效力，骚扰锥蝽可以被巨蝽和/或饰边锥蝽取代。
