Walters D R, Cowley T, McPherson A
Plant Science Department, Scottish Agricultural College, Auchincruive, UK.
FEMS Microbiol Lett. 1997 Aug 15;153(2):433-7. doi: 10.1111/j.1574-6968.1997.tb12607.x.
Biomass production by Aspergillus fumigatus was greatest at 40-45 degrees C and was associated with an increase in concentration of the diamine putrescine and activity of its biosynthetic enzyme ornithine decarboxylase. Concentrations of the other amines, cadaverine, spermidine and spermine were considerably lower than putrescine concentration and did not change significantly over the temperature range 20-50 degrees C. This is surprising in view of the greatly increased flux of label from ornithine through to spermidine at 45 and 50 degrees C, indicating an increased formation of this triamine. It is suggested that there was increased formation of spermidine derivatives at these temperatures. Interestingly, there was greatly increased formation of the higher homologues of cadaverine, aminopropylcadaverine and N,N'-bis(3-aminopropyl)cadaverine, in A. fumigatus at 45 and 50 degrees C.
烟曲霉的生物量产量在40 - 45摄氏度时最高，且与二胺腐胺浓度的增加及其生物合成酶鸟氨酸脱羧酶的活性相关。其他胺类，如尸胺、亚精胺和精胺的浓度远低于腐胺浓度，并且在20 - 50摄氏度的温度范围内没有显著变化。鉴于在45和50摄氏度时从鸟氨酸到亚精胺的标记通量大幅增加，表明该三胺的形成增加，这一现象令人惊讶。有人认为在这些温度下亚精胺衍生物的形成增加。有趣的是，在45和50摄氏度时，烟曲霉中尸胺的高级同系物，氨基丙基尸胺和N,N'-双(3-氨基丙基)尸胺的形成大幅增加。
