痰细胞学检查：作用有限。
Sputum cytology: a limited role.
作者信息
Gledhill A, Bates C, Henderson D, DaCosta P, Thomas G
机构信息
Harrogate General Hospital, UK.
出版信息
J Clin Pathol. 1997 Jul;50(7):566-8. doi: 10.1136/jcp.50.7.566.
AIMS
To determine the cost and sensitivity of sputum cytology in routine use and to determine when sputum cytology is most appropriate.
METHODS
A retrospective study, based on all sputum cytology requests received in five histopathology/cytopathology laboratories in Yorkshire from 1 January to 31 December 1993. Cytology findings were correlated with histological diagnosis or clinical outcome, and related to the speciality of the referring clinician.
RESULTS
Laboratory practice and performance was similar in all five centres. The average laboratory cost of sputum cytology was 26.93. The mean absolute sensitivity was 36% and the specificity was 99.6%. The majority of specimens was submitted by general physicians or geriatricians. The largest proportion of positive specimens were submitted by chest physicians.
CONCLUSIONS
Often sputum cytology is used inappropriately as a screening investigation on, or soon after, admission. In addition, it is used inappropriately before bronchoscopy. Sputum cytology should be limited to individuals in whom a histological diagnosis is desired, but in whom bronchoscopy is inappropriate or unsuccessful.
目的
确定常规使用痰细胞学检查的成本和敏感性，并确定何时痰细胞学检查最为合适。
方法
一项回顾性研究，基于1993年1月1日至12月31日在约克郡五个组织病理学/细胞病理学实验室收到的所有痰细胞学检查申请。将细胞学检查结果与组织学诊断或临床结果相关联，并与转诊临床医生的专业相关联。
结果
所有五个中心的实验室操作和表现相似。痰细胞学检查的平均实验室成本为26.93英镑。平均绝对敏感性为36%，特异性为99.6%。大多数标本由普通内科医生或老年病科医生提交。阳性标本比例最大的是由胸科医生提交的。
结论
痰细胞学检查常常被不恰当地用作入院时或入院后不久的筛查检查。此外，在支气管镜检查之前也被不恰当地使用。痰细胞学检查应仅限于那些需要组织学诊断，但支气管镜检查不合适或不成功的个体。
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