Schein O D, Tielsch J M, Munõz B, Bandeen-Roche K, West S
Department of Ophthalmology, Johns Hopkins University, Baltimore, Maryland, USA.
Ophthalmology. 1997 Sep;104(9):1395-401. doi: 10.1016/s0161-6420(97)30125-0.
To examine the distribution and association of dry eye symptoms, Schirmer test results, and rose bengal scores in a population-based sample of elderly Americans.
Population-based prevalence survey.
Involved were 2240 noninstitutionalized residents of Salisbury, Maryland, aged 65 years and older as of September 1993, and identified by the Health Care Financing Administration Medicare database.
A standardized dry eye symptom questionnaire, rose bengal scoring of ocular surface staining, and Schirmer tests.
Fourteen percent of participants reported one or more symptoms to be present often or all the time. The mean Schirmer score in the lower testing eye was 12.4 and 42% had a rose bengal score of 1 or greater. No significant differences by age, gender, or race were seen for symptoms, Schirmer, or rose bengal testing. No association was seen between lower Schirmer scores and presence of more frequent symptoms. Higher rose bengal scores were weakly associated with symptoms. The Schirmer and rose bengal test results, both individually and in combination, were insensitive in identifying individuals who had symptoms.
Although symptoms of ocular irritation are common among the elderly, these population-based data indicate that there is minimal overlap between individuals identified by questionnaire, Schirmer tests, and rose bengal scoring.
在以美国老年人群为基础的样本中，研究干眼症状、泪液分泌试验结果及孟加拉玫瑰红染色评分的分布情况及其相关性。
以人群为基础的患病率调查。
涉及1993年9月时年龄在65岁及以上、居住在马里兰州索尔兹伯里且未住机构的2240名居民，通过医疗保健财务管理局医疗保险数据库确定。
标准化干眼症状问卷、眼表染色的孟加拉玫瑰红评分及泪液分泌试验。
14%的参与者报告经常或一直存在一种或多种症状。较低测试眼的平均泪液分泌试验评分为12.4，42%的参与者孟加拉玫瑰红评分为1或更高。在症状、泪液分泌试验或孟加拉玫瑰红测试方面，年龄、性别或种族之间未见显著差异。较低的泪液分泌试验评分与更频繁症状的存在之间未见相关性。较高的孟加拉玫瑰红评分与症状呈弱相关。泪液分泌试验和孟加拉玫瑰红测试结果单独或联合使用时，在识别有症状个体方面均不敏感。
虽然眼部刺激症状在老年人中很常见，但这些基于人群的数据表明，通过问卷、泪液分泌试验和孟加拉玫瑰红评分所识别的个体之间重叠极少。
