Schelling U, Frank W, Will R, Romig T, Lucius R
Division of Parasitology, University of Hohenheim, Stuttgart, Germany.
Ann Trop Med Parasitol. 1997 Mar;91(2):179-86. doi: 10.1080/00034983.1997.11813128.
In order to evaluate the applicability of anthelminthic treatment of wild foxes (Vulpes vulpes) to limit their infection with Echinococcus multilocularis, bait pellets, each containing 50 mg praziquantel, were repeatedly distributed in an area of 566 km2 where many foxes are infected, in southern Germany. After six baiting campaigns (15-20 baits/km2) over a period of 14 months, the prevalence of the cestode in foxes, initially 32%, had fallen to 4%. The effect was most pronounced in the central part of the treated area, where no positive fox was found in the 2 months before the end of the trial. The study was controlled for other factors that could influence the parasite's prevalence, such as the availability of intermediate hosts. While the potential of this baiting method to remove E. multilocularis from wild hosts has been demonstrated, the question of its long-term efficacy and other unresolved problems have to be addressed by consecutive studies before routine application can be recommended.
为了评估对野生狐狸（赤狐）进行驱虫治疗以限制其感染多房棘球绦虫的适用性，在德国南部一个面积为566平方公里、有许多狐狸感染的区域，反复投放了每粒含50毫克吡喹酮的诱饵丸。在14个月的时间里进行了六次诱饵投放活动（每平方公里投放15 - 20个诱饵）后，狐狸体内该绦虫的感染率最初为32%，已降至4%。这种效果在治疗区域的中部最为明显，在试验结束前的两个月里，该区域未发现呈阳性的狐狸。该研究对可能影响寄生虫感染率的其他因素进行了控制，如中间宿主的可得性。虽然这种诱饵投放方法从野生宿主中清除多房棘球绦虫的潜力已得到证明，但在推荐常规应用之前，其长期疗效问题及其他未解决的问题必须通过后续研究加以解决。
