Ostman J, Anneroth G, Gustafsson H, Tavelin B
Department of Oral Pathology, Umeå University, Sweden.
Oral Oncol. 1997 May;33(3):169-76. doi: 10.1016/s0964-1955(96)00077-2.
Epidemiological data from the Swedish Cancer Registry of new cases of malignant major and accessory salivary gland tumors in Sweden between 1960 and 1989 are presented, including the total number and the age-standardised incidence rate per 1 million population, by site and sex, I(s). An analysis of the various histopathological types of malignant salivary gland tumours in the different sublocations is also given. A comparison is made between the three 10-year periods 1960-1969, 1970-1979 and 1980-1989 regarding total number and I(s). The total number of new malignant major salivary gland tumors was 2557, representing approximately 85 new cases per year and 0.3% of all new diagnosed cancers in Sweden. In addition, approximately 25 new cases per year of malignant accessory salivary gland tumors were reported. If all malignant salivary gland tumours were considered, the most common location was found in the parotid glands with a relative frequency of 57.5%, and the next most common site was malignant accessory salivary gland tumours with 22.6%. I(s) was 10.2 for the major and 3.0 for the accessory salivary glands. No major difference between the examined 10-year periods was found concerning the relative frequency, and no statistically significant difference in I(s) was found between the examined 10-year periods, except for a statistically significant decrease in the I(s) between the time periods 1960-1969 and 1980-1989 for the multiple or unspecified malignant salivary glands from 0.5 to 1.4. A difference in the distribution of various histopathological types of malignant salivary gland tumours was observed between the different time periods. This was particularly valid for the diagnoses adenoid cystic carcinomas and mucoepidermoid carcinomas which increased in number and the diagnosis malignant salivary gland tumours of mixed type, which decreased in number during the examined time periods.
本文呈现了瑞典癌症登记处1960年至1989年间瑞典主要和副唾液腺恶性肿瘤新发病例的流行病学数据，包括按部位和性别划分的每100万人口中的总数和年龄标准化发病率I(s)。还对不同亚部位的恶性唾液腺肿瘤的各种组织病理学类型进行了分析。对1960 - 1969年、1970 - 1979年和1980 - 1989年这三个十年期的总数和I(s)进行了比较。主要唾液腺恶性肿瘤新发病例总数为2557例，每年约85例，占瑞典所有新诊断癌症的0.3%。此外，每年报告约25例副唾液腺恶性肿瘤新发病例。如果考虑所有恶性唾液腺肿瘤，最常见的部位是腮腺，相对频率为57.5%，其次是副唾液腺恶性肿瘤，为22.6%。主要唾液腺的I(s)为10.2，副唾液腺为3.0。在所检查的十年期之间，相对频率没有发现重大差异，I(s)也没有发现统计学上的显著差异，除了1960 - 1969年和1980 - 1989年期间，多灶性或未明确的恶性唾液腺肿瘤的I(s)从0.5降至1.4有统计学显著下降。在不同时间段观察到恶性唾液腺肿瘤各种组织病理学类型的分布存在差异。这在腺样囊性癌和黏液表皮样癌的诊断中尤为明显，其数量增加，而混合型恶性唾液腺肿瘤的诊断数量在检查时间段内减少。
