Gazvani M R, Buckett W, Luckas M J, Aird I A, Hipkin L J, Lewis-Jones D I
Reproductive Medicine Unit, Liverpool Women's Hospital, UK.
Hum Reprod. 1997 Aug;12(8):1706-8. doi: 10.1093/humrep/12.8.1706.
As well as athletes and competitive body builders, recreational body builders attending gymnasia are known to abuse anabolic steroids, using doses from 10- to 40-fold above physiological levels. Androgenic steroids induce hypogonadotrophic hypogonadism with associated azoospermia, leading to infertility. Little literature exists on the treatment of steroid-induced azoospermia following the cessation of abuse. We present four cases of steroid-induced azoospermia, its conservative management and eventual return of normal semen density.
除了运动员和竞技健美运动员外,在健身房锻炼的业余健美运动员也存在滥用合成代谢类固醇的情况,其使用剂量比生理水平高出10至40倍。雄激素类固醇会导致低促性腺激素性性腺功能减退并伴有无精子症,从而导致不育。关于滥用类固醇停止后类固醇诱导的无精子症的治疗,相关文献较少。我们报告了4例类固醇诱导的无精子症病例、其保守治疗方法以及精液密度最终恢复正常的情况。