Wu J M, Leung S W, Wang C J, Chui C S
Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital, Taiwan.
Int J Radiat Oncol Biol Phys. 1997 Sep 1;39(2):521-8. doi: 10.1016/s0360-3016(97)00141-7.
A technique for whole-body electron therapy with the patient in a lying position has been developed. This technique allows Total Skin Electron Therapy (TSET) for those patients who were previously unable to be treated in a conventional standing position.
This study was carried out on a Varian 2100C linear accelerator with a 6 MeV high dose rate electron beam. The collimator was open to a width of 36 x 36 cm. There were two main procedures, with six dual-field techniques: 1) two static AP/PA vertical dual fields (VDF): the patient laid on the floor transversely under the collimator when the gantry was in a vertical position. A 0.6 cm acrylic board was placed 15 cm away from the patient, then the gantry was rotated 25 degrees clockwise and counterclockwise to treat the patient in the supine and prone positions, respectively. 2) Four oblique junction fields (OJF): the patient laid on the floor in a prone and supine position parallel to the wave guide at (227 - body thickness x tan 60 degrees) cm away from the vertical axis of the gantry, then the gantry was rotated 60 degrees toward the patient. A 0.6 cm acrylic board was placed 15 cm away from the patient perpendicular to the beam. The patient was move along the field central axis. It allowed the patient's body to be within the 160 cm effective treatment profile. When the patient's body axis move 5 degrees toward the lateral side of the field central axis, we could obtain a better dose distribution in the vertex of the scalp and the soles of the feet. The angle of the VDF was measured by chamber detectors to obtain the effective treatment profile. Likewise, the optimal profile for the OJF was determined by the same procedures. The Rando phantom was used to measure the superficial dose of the body.
The dimension of effective treatment profile for the VDF was 188 x 72 cm at 87% dose level For the OJF, we had to move the patient along the field central axis to obtain the effective treatment profile in a 180 x 85 cm dimension at a 87% dose level. The vertex and sole dose measured in this setup was in the range of 80-88%.
The empirical data showed that the lying-on position for TSET was technically feasible. The dose distribution in the body surface was also compatible with the Stanford standing technique. The nonambulatory skin malignancy patient can be treated in a comfortable and reproducible position.
已开发出一种患者处于卧位的全身电子治疗技术。该技术使得那些先前无法以传统站立位接受治疗的患者能够接受全身皮肤电子治疗(TSET)。
本研究在配备6 MeV高剂量率电子束的瓦里安2100C直线加速器上进行。准直器开口宽度为36×36 cm。有两个主要程序,采用六种双野技术:1)两个静态前后/后前垂直双野(VDF):当机架处于垂直位置时,患者横向躺在准直器下方的地板上。在距患者15 cm处放置一块0.6 cm厚的丙烯酸板,然后机架分别顺时针和逆时针旋转25度,以分别在仰卧位和俯卧位治疗患者。2)四个斜交连接野(OJF):患者俯卧位和仰卧位躺在地板上,与波导平行,距离机架垂直轴(227 - 身体厚度×tan 60度)cm,然后机架向患者旋转60度。在距患者15 cm处垂直于射束放置一块0.6 cm厚的丙烯酸板。患者沿野中心轴移动。这使得患者身体处于160 cm有效治疗范围内。当患者身体轴朝野中心轴外侧移动5度时,我们可以在头皮顶点和脚底获得更好的剂量分布。通过电离室探测器测量VDF的角度以获得有效治疗范围。同样,通过相同程序确定OJF的最佳范围。使用兰多人体模型测量身体的表面剂量。
VDF在87%剂量水平下的有效治疗范围尺寸为188×72 cm。对于OJF,我们必须让患者沿野中心轴移动,以在87%剂量水平下获得尺寸为180×85 cm的有效治疗范围。在此设置下测量的顶点和脚底剂量在80 - 88%范围内。
经验数据表明,TSET的卧位在技术上是可行的。体表的剂量分布也与斯坦福站立技术兼容。不能行走的皮肤恶性肿瘤患者可以在舒适且可重复的体位下接受治疗。