Davisson M T
Jackson Laboratory, Bar Harbor, Maine 04609, USA.
Transgenic Res. 1997 Sep;6(5):309-19. doi: 10.1023/a:1018466830035.
The unique identification of genes and mouse strains is critical to their identification in research and in the scientific literature. Rules for genetic nomenclature in mice have existed since the 1940s. The latest complete revision of the rules was approved by the International Committee on Standardized Genetic Nomenclature for Mice in November, 1993. Minor revisions have occurred since. The complete, current rules are available on-line from The Jackson Laboratory's Mouse Genome Database (MGD), URL: http:(+)+www.informatics.jax.org. A printed version appeared in Mouse Genome 92 (2), June, 1994, and in Genetic Variants and Strains of the Laboratory Mouse, 3rd edition (Committee on Standardized Genetic Nomenclature for Mice, 1996a,b,c). The excerpted version below gives the general guidelines for naming and symbolizing mouse genes, transgenes and transgenic strains, targeted mutations and DNA markers. More detailed guidelines, including revisions as they are made, may be found at the MGD Web site given above. Subparagraphs are numbered as in the complete guidelines so that the user can refer easily from this excerpted version to the full text. Textual references to paragraphs not included here may be found in the full text as well.
基因和小鼠品系的独特标识对于在研究及科学文献中识别它们至关重要。自20世纪40年代起就存在小鼠基因命名规则。规则的最新全面修订于1993年11月获国际小鼠标准化遗传命名委员会批准。此后有过一些小修订。完整的现行规则可从杰克逊实验室的小鼠基因组数据库(MGD)在线获取,网址:http:(+)+www.informatics.jax.org。1994年6月的《小鼠基因组》第92卷第2期以及《实验小鼠的遗传变异与品系》第3版(小鼠标准化遗传命名委员会,1996a、b、c)刊载了印刷版本。以下节选版本给出了小鼠基因、转基因和转基因品系、靶向突变及DNA标记命名和符号表示的一般指南。更详细的指南,包括修订内容,可在上述MGD网站找到。各小段编号与完整指南一致,以便用户能轻松从这个节选版本查阅全文。此处未包含段落的文字引用在全文中也可找到。