Johnstone M A
Department of Ophthalmology, Swedish Hospital, Medical Center. 767467,
Am J Ophthalmol. 1997 Oct;124(4):544-7. doi: 10.1016/s0002-9394(14)70870-0.
To describe hypertrichosis and increased pigmentation of eyelashes associated with topical latanoprost usage.
Patients using unilateral topical latanoprost for glaucoma were examined for evidence of hypertrichosis and pigmentation of eyelashes and adjacent hair in the latanoprost-treated eye compared with the nontreated control eye.
In 43 patients receiving unilateral topical latanoprost, hypertrichosis involved ipsilateral terminal eyelashes and regional intermediate hairs of the upper and lower eyelid as well as vellus hair of the lower eyelid skin. Differences in hair appearance between the latanoprost-treated eye and the nontreated control eye included increased number, length, thickness, curvature, and pigmentation.
Latanoprost-treated eyes develop hypertrichosis and increased pigmentation in the region of treatment. Patients may benefit from being made aware of this side effect.
描述与局部使用拉坦前列素相关的多毛症及睫毛色素沉着增加的情况。
对使用单侧局部拉坦前列素治疗青光眼的患者进行检查，观察拉坦前列素治疗眼与未治疗对照眼相比，睫毛及邻近毛发出现多毛症和色素沉着的证据。
在43例接受单侧局部拉坦前列素治疗的患者中，多毛症累及同侧终末睫毛、上下眼睑的区域中间毛发以及下眼睑皮肤的毳毛。拉坦前列素治疗眼与未治疗对照眼之间毛发外观的差异包括数量增加、长度增加、厚度增加、弯曲度增加和色素沉着增加。
拉坦前列素治疗的眼睛在治疗区域会出现多毛症和色素沉着增加。让患者了解这种副作用可能会使其受益。
