Niessen F B, Spauwen P H, Kon M
Department of Plastic Surgery, University Hospital, Utrecht, The Netherlands.
Ann Plast Surg. 1997 Sep;39(3):254-60. doi: 10.1097/00000637-199709000-00006.
The development of hypertrophic scars and keloids is an unsolved problem in the process of wound healing. There are indications that inflammation plays an important role in this process, but its exact mechanism remains unclear. In this study the amount of inflammation and the development of hypertrophic scars and keloids was investigated in inframammary skin incisions sutured with synthetic absorbable suture materials: a monofilamentous suture (Monocryl) compared with a multifilamentous suture (Vicryl-rapide). In 81 breast reduction patients Monocryl (N = 28) has proved to give significantly smaller, less reactive scars with a lower tendency toward hypertrophic scar formation compared with Vicryl-rapide (N = 53).
肥厚性瘢痕和瘢痕疙瘩的形成是伤口愈合过程中一个尚未解决的问题。有迹象表明炎症在这一过程中起重要作用，但其确切机制仍不清楚。在本研究中，对使用合成可吸收缝合材料缝合的乳房下皮肤切口处的炎症程度以及肥厚性瘢痕和瘢痕疙瘩的形成情况进行了研究：将单丝缝合线（爱惜康单股缝线）与多丝缝合线（快薇乔）进行比较。在81例乳房缩小术患者中，与快薇乔（n = 53）相比，爱惜康单股缝线（n = 28）已被证明能产生明显更小、反应性更低的瘢痕，形成肥厚性瘢痕的倾向也更低。
