Evans B M
J Neurol Neurosurg Psychiatry. 1976 Apr;39(4):392-402. doi: 10.1136/jnnp.39.4.392.
The EEG changes, with associated cardiorespiratory phenomena and, where possible, postmortem findings, are described in six patients in coma, with some reference to other similar cases. Spontaneously occurring periodic changes were observed at varying intervals between 20 s and 4 min but most commonly at 1/2-2 min. These involved simultaneous cardiorespiratory, EEG, and somatic motor phenomena related to changes in the level of arousal. It is suggested that a physiological periodicity of the arousal mechanisms exists which may be of importance in the understanding of the pathophysiology of comatose states.
本文描述了6例昏迷患者的脑电图变化，以及相关的心肺现象，并在可能的情况下提及了尸检结果，同时也参考了其他一些类似病例。观察到自发出现的周期性变化，其间隔时间在20秒至4分钟之间不等，但最常见的是在半分钟至2分钟之间。这些变化涉及与觉醒水平改变相关的同时发生的心肺、脑电图和躯体运动现象。有人提出，觉醒机制存在一种生理周期性，这可能对理解昏迷状态的病理生理学具有重要意义。
