Bronner-Fraser M
Division of Biology, California Institute of Technology, Pasedena 91125, USA.
Adv Pharmacol. 1998;42:883-7. doi: 10.1016/s1054-3589(08)60888-1.
The data summarized here indicate that (1) the neural crest can arise by means of inductive interaction between the neural and nonneural ectoderm; (2) initially, progenitor cells are multipotent, having the potential to form multiple ectodermal derivatives (epidermis, neural crest, and neural tube derivatives); and (3) with time, the precursors become progressively restricted to form neural crest derivatives and eventually to individual phenotypes.
（1）神经嵴可通过神经外胚层和非神经外胚层之间的诱导相互作用产生；（2）最初，祖细胞具有多能性，有可能形成多种外胚层衍生物（表皮、神经嵴和神经管衍生物）；（3）随着时间的推移，前体细胞逐渐受限，形成神经嵴衍生物，并最终形成个体表型。
