McFarlane A, Scott J S
J Med Genet. 1976 Jun;13(3):208-11. doi: 10.1136/jmg.13.3.208.
A study of 1045 twin gestations with regard to known or likely zygosity and the incidence of pre-eclampsia/eclampsia failed to reveal differences between known dizygous twins and like-sex 'presumed' and 'estimated' monozygous twins except in the 'estimated' data for multigravidae. There was a threefold increase in the incidence for twins as opposed to singleton pregnancies. These results are discussed in relation to increased conceptus-mother antigenic differences. It is suggested that the risk of gestosis in twin pregnancy involves more than a summation of that operating in two singleton pregnancies.
一项针对1045例双胎妊娠的研究，涉及已知或可能的合子性以及先兆子痫/子痫的发生率，结果显示，已知的双卵双胎与同性别的“推定”和“估计”单卵双胎之间没有差异，除非是多产妇的“估计”数据。与单胎妊娠相比，双胎妊娠的发生率增加了两倍。这些结果结合受精卵与母亲抗原性差异的增加进行了讨论。有人提出，双胎妊娠中发生妊娠中毒症的风险不仅仅是两个单胎妊娠中风险的总和。
