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Synthesis of Tn and sialyl Tn antigen-lipid A analog conjugates for synthetic vaccines.

作者信息

Miyajima K, Nekado T, Ikeda K, Achiwa K

机构信息

School of Pharmaceutical Sciences, University of Shizuoka, Japan.

出版信息

Chem Pharm Bull (Tokyo). 1997 Sep;45(9):1544-6. doi: 10.1248/cpb.45.1544.

Abstract

Conjugates of Tn and sialyl Tn antigen with N-teradecanoyl L-seryl-beta-alanine-containing D-glucosamine derivatives structurally related to lipid A as an immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers or HIV.

摘要

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