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[丙型肝炎在医护人员中的职业医学意义]

[Occupational medicine significance of hepatitis C in health care employees].

作者信息

Hofmann F, Michaelis M, Rieger M A, Hasselhorn H M, Berthold H

机构信息

Bergische Universität/Gesamthochschule Wuppertal, Lehrstuhl für Arbeitsphysiologie, Arbeitsmedizin und Infektionsschutz.

出版信息

Gesundheitswesen. 1997 Jul;59(7):452-60.

PMID:9333386
Abstract

Transmission of Hepatitis C virus (HCV) is similar to the one observed with hepatitis B virus. The most important route of infection in health care personnel is by needlestick injury. In the course of a literature review 44 publications on HCV prevalence or incidence among hospital employees were studied and an overall transmission incidence of 2.2% was found. As none of the publications dealt with the problem of chronic Hepatitis C, 245 persons with elevated transaminases occupied Freiburg University Hospital were tested for HCV antibodies. 3 out of 82 non-medical professionals and 19 out of 163 health care workers were anti HCV positive (RR = 3.22; p < 0.05). Charwomen in medical departments, nurses and dentists had a higher relative risk than physicians and technical assistants. As no HCV vaccine is available the only way of HCV-prevention is compliance with universal precautions.

摘要

丙型肝炎病毒(HCV)的传播与乙型肝炎病毒的传播情况相似。医护人员最重要的感染途径是针刺伤。在一次文献综述过程中,研究了44篇关于医院员工中HCV患病率或发病率的出版物,发现总体传播发生率为2.2%。由于没有出版物涉及慢性丙型肝炎问题,对弗赖堡大学医院245名转氨酶升高的人员进行了HCV抗体检测。82名非医学专业人员中有3人以及163名医护人员中有19人抗HCV呈阳性(相对危险度=3.22;p<0.05)。医疗部门的清洁女工、护士和牙医的相对危险度高于医生和技术助理。由于没有可用的HCV疫苗,预防HCV的唯一方法是遵守普遍预防措施。

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