Prassler R, Dormann A J, Vallentin J, Wigginghaus B, Huchzermeyer H
Medizinische Klinik, Klinikum Minden.
Dtsch Med Wochenschr. 1997 Sep 5;122(36):1065-9. doi: 10.1055/s-2008-1047729.
To obtain normal values of 24-hour manometry of the oesophagus.
Oesophageal pressures were measured in 41 healthy volunteers who had given informed consent. Recordings were made for 24 hours via a two-channel catheter in 27 and via a 4-channel one in 14 subjects. The catheter orifices were 5 and 15 cm respectively 5, 10, 15 and 20 cm above the lower oesophageal sphincter.
Median of contractions was 1523 at 5 cm and 1500 at 15 cm (1635 at 10 cm and 2135 at 20 cm) contraction amplitudes were 31 mm Hg at 5 cm, 26 mm Hg at 15 cm; 26 mm Hg at 10 cm and 37 mm Hg at 20 cm. On average 44% of the contractions were propulsive, 17% simultaneous and 30% nonpropulsive, the remainder not clearly defined. Neither age nor sex had a significant influence on the results. Motor activity was reduced during sleep. During eating the number of contractions, their amplitude and propulsive force increased.
The listed measurements, by defining normal values, make it possible to diagnose hypo- and hypermotility of the oesophagus during long-time manometry. Two-point measurement is sufficient for assessing the smooth-muscle component.
获取食管24小时测压的正常值。
对41名签署知情同意书的健康志愿者进行食管压力测量。27名受试者通过双腔导管、14名受试者通过四腔导管进行24小时记录。导管开口分别位于食管下括约肌上方5厘米、10厘米、15厘米和20厘米处，距离分别为5厘米和15厘米。
5厘米处收缩中位数为1523次，15厘米处为1500次（10厘米处为1635次，20厘米处为2135次）；收缩幅度在5厘米处为31毫米汞柱，15厘米处为26毫米汞柱，10厘米处为26毫米汞柱，20厘米处为37毫米汞柱。平均44%的收缩为推进性，17%为同步性，30%为非推进性，其余情况不明确。年龄和性别对结果均无显著影响。睡眠期间运动活性降低。进食期间收缩次数、幅度和推进力增加。
通过确定正常值，所列测量结果能够在长时间测压过程中诊断食管动力不足和亢进。两点测量足以评估平滑肌成分。
