Ptácková B
Neoplasma. 1976;23(2):215-21.
During the course of 16 years, i. e. from 1953 to 1968 inclusively, a total of 2111 patients with carcinoma of the uterine cervix were treated at the Oncological Institute in Brno. Of these, 1829 patients, i. e. 86.6% were irradiated, 282, i. e. 13.4% underwent primarily a radical excision and subsequently were irradiated. During the past years, approximately 95% of all such patients are being given radical irradiation. The mean age is 52.7 years, the sixth decade being numerically the highest in incidence -- 27.4%. The distribution pattern according to the tumor stage: I -- 29.3%, II -- 14.3%, III -- 48.2%, IV -- 8.2%. This distribution remained practically unchanged over the follow-up period of 16 years. The fundamental method treatment of practically 87% of all the patients was actinotherapy consisting in a combined application of radium and X-rays. Of the total number of 2111 patients, 1298, i. e. 61.5% have survived 5 years without any symptoms of the disease, 966 patients, i. e. 59.0% (out of a total of 1671 patients) survived 10 years. The five-year survival symptom-free period for the various stages ia as follows: I -- 82.5%, II -- 77.1%, III -- 52.8% and IV -- 9.8%. A comparison of the results of treatment in patients radically irradiated and those primarily operated upon then subsequently irradiated, i. e. in 619 patients of stage I showed the 5-year recovery to be superior by almost 4% in the former than in the latter group --84.1% as against 80.3%. Over the last 6 years of the follow-up, i. e. 1962--1968, this difference went up to 6.0% in favour of those radically irradiated--85.1% as against 79.2%. An increasing mortality rate due to carcinoma is noted with advancing age.
在16年期间，即从1953年至1968年（含），布尔诺肿瘤研究所共治疗了2111例子宫颈癌患者。其中，1829例患者（即86.6%）接受了放射治疗，282例（即13.4%）首先接受了根治性切除，随后接受了放射治疗。在过去几年中，所有此类患者中约95%接受了根治性放射治疗。平均年龄为52.7岁，发病率最高的年龄段是第六个十年——27.4%。根据肿瘤分期的分布情况：I期——29.3%，II期——14.3%，III期——48.2%，IV期——8.2%。在16年的随访期内，这种分布情况基本保持不变。实际上，所有患者中约87%的基本治疗方法是放射疗法，即镭和X射线联合应用。在2111例患者总数中，1298例（即61.5%）已存活5年且无任何疾病症状，966例患者（即1671例患者总数中的59.0%）存活了10年。各期的五年无病生存期如下：I期——82.5%，II期——77.1%，III期——52.8%，IV期——9.8%。对接受根治性放射治疗的患者与首先接受手术然后再接受放射治疗的患者（即619例I期患者）的治疗结果进行比较，结果显示，前者的5年康复率比后者高出近4%——分别为84.1%和80.3%。在随访的最后6年，即1962年至1968年，这种差异增至6.0%，有利于接受根治性放射治疗的患者——分别为85.1%和79.2%。随着年龄的增长，因癌症导致的死亡率呈上升趋势。
