大鼠肾脏的脂质组成。

Lipid composition of the rat kidney.

作者信息

Müller M M, Kaiser E, Bauer P, Scheiber V, Hohenegger M

出版信息

Nephron. 1976;17(1):41-50. doi: 10.1159/000180709.

Abstract

The lipid fractions free fatty acids, triglycerides, cholesterol, cholesterol esters and phospholipids of rat kidney cortex, outer and inner medulla were analyzed by thin-layer chromatography. The concentrations of 23 individual fatty acids in the lipid fractions of each zone were determined by gas chromatography; 14 of them were evaluated by an analysis of variance. For most of the lipid fractions a corticomedullary concentration gradient was found, the highest concentrations occurring in the cortex. The lipid classes primarily determined the pattern of individual fatty acid concentrations. A significant concentration difference between the three zones only existed for 4 of 14 fatty acids. Long chain fatty acids were found in a higher concentration in the phospholipids of cortex and outer medulla (about 95%) in comparison to the inner medulla (65%).

摘要

采用薄层色谱法分析了大鼠肾皮质、外髓和内髓中的游离脂肪酸、甘油三酯、胆固醇、胆固醇酯和磷脂等脂质组分。通过气相色谱法测定了每个区域脂质组分中23种单个脂肪酸的浓度；其中14种通过方差分析进行评估。对于大多数脂质组分，发现了皮质-髓质浓度梯度，最高浓度出现在皮质中。脂质类别主要决定了单个脂肪酸浓度的模式。14种脂肪酸中只有4种在三个区域之间存在显著的浓度差异。与内髓（65%）相比，皮质和外髓的磷脂中长链脂肪酸的浓度更高（约95%）。