[大鼠肾上腺自溶过程中内源性脂质的分解代谢变化]
[Catabolic changes in endogenous lipids in rat adrenal glands during autolysis].
作者信息
Gribanov G A
出版信息
Vopr Med Khim. 1977 May-Jun(3):381-5.
Alterations in lipid composition of rat adrenal glands were studied at various periods of autolysis by means of micro-thin layer chromatography. Phospholipids, cholesterol and its esters proved to be the most labile lipid fractions of the tissue. At early period of autolysis (4 hrs) content of total lipids was decreased mainly due to lowering in amount of phospholipids, cholesterol and its esters and only slightly - to lowering in content of free fatty acids. In subsequent necrobiotic degradation of adrenal gland tissue (10 hrs) the increase in content of total lipids was related to the distinct elevation in amount of free fatty acids and glycerides. Mechanisms of the phenomenon observed are discussed.
通过微薄层色谱法研究了大鼠肾上腺在自溶不同阶段的脂质组成变化。磷脂、胆固醇及其酯被证明是该组织中最不稳定的脂质成分。在自溶早期（4小时），总脂质含量下降主要是由于磷脂、胆固醇及其酯的量减少，而游离脂肪酸含量仅略有下降。在肾上腺组织随后的渐进性坏死降解过程中（10小时），总脂质含量的增加与游离脂肪酸和甘油酯量的明显升高有关。文中讨论了所观察到现象的机制。
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