Davis D P, Bramwell K J, Hamilton R S, Williams S R
Department of Emergency Medicine, University of California at San Diego Medical Center and Mercy Hospital and Medical Center, 92103-8676, USA.
J Emerg Med. 1997 Sep-Oct;15(5):653-67. doi: 10.1016/s0736-4679(97)00145-5.
Ethylene glycol is commonly found in automobile antifreeze and a variety of other commercial products. Ingestion of ethylene glycol, either accidentally or in a suicide attempt, is characterized by severe acidosis, calcium oxalate crystal formation and deposition, and a wide variety of end organ effects that may be fatal. We present a case of a patient who ingested a massive amount of ethylene glycol in a suicide attempt and yet survived with minimal sequelae. A comprehensive review of the literature on the pathology and pathophysiology of ethylene glycol toxicity on each organ system is provided, along with information on diagnosis and current treatment recommendations.
乙二醇常见于汽车防冻液及多种其他商业产品中。意外摄入或企图自杀而摄入乙二醇的情况，其特征为严重酸中毒、草酸钙晶体形成与沉积，以及可能致命的多种终末器官效应。我们报告一例患者，其在自杀企图中摄入大量乙二醇，但最终存活且后遗症极少。本文提供了关于乙二醇对各器官系统毒性的病理学和病理生理学的文献综述，以及诊断信息和当前的治疗建议。
