Hann Gayle, Duncan Dana, Sudhir Gopakumar, West Peter, Sohi Dalbir
Paediatrics Department, North Middlesex Hospital, London, UK.
BMJ Case Rep. 2012 Mar 27;2012:bcr0720114509. doi: 10.1136/bcr.07.2011.4509.
This case report describes the presentation and management of a 2-year-old child who ingested a potentially fatal amount of ethylene glycol (EG). There are few published cases worldwide of EG poisoning in children managed with fomepizole. All cases described in the literature were managed in a paediatric intensive care unit. In this case, the child presented irritable, pale and confused with high anion gap metabolic acidosis. As there were no paediatric intensive care beds available in the region, the child was successfully managed in a high dependency area in our district general hospital. The child fully recovered and was discharged home in 7 days. The authors believe that multi-disciplinary team management and the use of fomepizole contributed to the positive outcome and this case raised many useful learning points.
本病例报告描述了一名2岁儿童摄入可能致命剂量乙二醇（EG）后的临床表现及治疗情况。全球范围内，使用甲吡唑治疗儿童乙二醇中毒的已发表病例很少。文献中描述的所有病例均在儿科重症监护病房进行治疗。在本病例中，患儿表现为烦躁、面色苍白、意识模糊，伴有高阴离子间隙代谢性酸中毒。由于该地区没有儿科重症监护床位，患儿在我们区综合医院的高依赖病房成功接受了治疗。患儿完全康复，并于7天后出院。作者认为，多学科团队管理和甲吡唑的使用促成了这一积极结果，该病例还提出了许多有益的经验教训。
