Rauh G, Gross M
Medizinische Poliklinik, Klinikum Innenstadt der Ludwig-Maximilians-Universität Pettenkoferstr. 8a Munich D-80336 Germany +49 89/5160 3511 +49 89/5160 4439.
Eur J Med Res. 1997 Oct 30;2(10):425-7.
A patient with osteolysis of the right hand after a metatarsal fracture at the age of 12 years is reported. The osteolysis progressed until the age of 21 years and was stable until the age of 59 years, when the patient died from a metastatic colon cancer. The article discusses the clinical, radiographic, and histologic features, and prognosis of idiopathic osteolysis (Gorham-Stout disease). Gorham-Stout disease is characterized by a non-familial, histological benign vascular proliferation producing lysis of the bone. The therapeutic options of Gorham-Stout disease is limited; radiotherapy has been used with success in single cases. Usually, the disease undergoes spontaneous arrest, as it occurred in our patient.
本文报告了一名12岁时跖骨骨折后右手出现骨质溶解的患者。骨质溶解一直进展到21岁，之后保持稳定，直到59岁患者死于转移性结肠癌。本文讨论了特发性骨质溶解（戈勒姆-斯托特病）的临床、影像学和组织学特征以及预后。戈勒姆-斯托特病的特点是一种非家族性的、组织学上良性的血管增生导致骨质溶解。戈勒姆-斯托特病的治疗选择有限；放射治疗在个别病例中取得了成功。通常，该病会自行停止发展，就像我们的患者那样。
