Othman Saleh
Department of Radiology and Medical Imaging, King Khalid University Hospital and College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Indian J Nucl Med. 2010 Jan;25(1):23-4. doi: 10.4103/0972-3919.63596.
Gorham's (vanishing bone) disease is an extremely rare condition of the bone. The diagnosis is usually made on the basis of the characteristic history of osteolysis and failure of bone healing in conjunction with the histological findings of marrow fibrosis and increased vascularity. When the disease is established, an X-ray and magnetic resonance imaging show complete loss of affected bone. There are very few reports found in literature on bone scan appearance of the disease. A bone scan of a 24-year-old female patient with known Gorham's disease revealed absence of tracer uptake in the right iliac bone, right sacroiliac joint, and part of the right ischial pubic rami, which matched the radiographic abnormalities. Consequently this disease should be added to the gamut of cold defects seen on bone scan.
戈勒姆病（骨质消失症）是一种极为罕见的骨骼疾病。诊断通常基于骨质溶解的典型病史、骨愈合失败，并结合骨髓纤维化和血管增多的组织学表现。确诊后，X 线和磁共振成像显示受累骨骼完全消失。关于该病骨扫描表现的文献报道极少。一名已知患有戈勒姆病的 24 岁女性患者的骨扫描显示，右侧髂骨、右骶髂关节和部分右侧坐骨耻骨支无示踪剂摄取，这与影像学异常相符。因此，该病应被列入骨扫描所见的冷区缺损范围。
