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健康与疾病状态下A组β溶血性链球菌与口咽上皮的选择性附着

Selective attachment of beta-haemolytic streptococci group A to oropharyngeal epithelium in health and disease.

作者信息

Lilja M, Myklebust R, Räisänen S, Stenfors L E

机构信息

Department of Otolaryngology, University of Tromsø, Norway.

出版信息

Acta Otolaryngol. 1997 Sep;117(5):744-9. doi: 10.3109/00016489709113471.

DOI:10.3109/00016489709113471
PMID:9349874
Abstract

Localization and semiquantification of beta-haemolytic streptococci, Group A (GABHS), GABHS attachment and general bacterial attachment to epithelial cells (bacterial number and morphology) were studied during GABHS-positive acute tonsillitis and pharyngitis infections and among healthy GABHS carriers. Samples were collected from various areas of the oropharynx (palatine tonsils, posterior oropharyngeal wall, palatoglossal arch and buccal mucosa). During acute tonsillitis and pharyngitis, GABHS grew in samples obtained from the palatine tonsils and posterior oropharyngeal wall. The ratio of GABHS colonies to other aerobic colonies increased, and GABHS became attached to epithelial cells of both palatine tonsils and posterior oropharyngeal wall. In GABHS carriers, GABHS were found mainly on the palatine tonsils, but these microorganisms were not attached to the epithelium. Overall bacterial attachment to tonsillar and oropharyngeal epithelial cells increased during active tonsillitis and pharyngitis.

摘要

在A组β溶血性链球菌(GABHS)阳性的急性扁桃体炎和咽炎感染期间以及健康的GABHS携带者中,研究了GABHS的定位和半定量、GABHS与上皮细胞的附着以及一般细菌与上皮细胞的附着(细菌数量和形态)。样本取自口咽的不同区域(腭扁桃体、口咽后壁、腭舌弓和颊黏膜)。在急性扁桃体炎和咽炎期间,GABHS在从腭扁桃体和口咽后壁获得的样本中生长。GABHS菌落与其他需氧菌落的比例增加,并且GABHS附着于腭扁桃体和口咽后壁的上皮细胞。在GABHS携带者中,GABHS主要存在于腭扁桃体上,但这些微生物未附着于上皮。在活动性扁桃体炎和咽炎期间,细菌与扁桃体和口咽上皮细胞的总体附着增加。

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