豚鼠中由1,2 - 二羟基苯（儿茶酚）诱导的5 - 羟色胺与肌阵挛
5-Hydroxytryptamine and myoclonus induced by 1,2-di-hydroxybenzene (catechol) in the guinea-pig.
作者信息
Chadwick D, Jenner P, Marsden C D
出版信息
Br J Pharmacol. 1979 Jul;66(3):358-60. doi: 10.1111/j.1476-5381.1979.tb10837.x.
Abstract
Myoclonus induced by catechol in the guinea-pig is not altered by manipulation of cerebral 5-hydroxytryptamine (5-HT). The administration of catechol does not alter brain levels of 5-HT or its metabolite 5-hydroxyindole acetic acid. This form of myoclonus therefore is not of relevance to the 5-HT-sensitive post-anoxic action myoclonus occurring in man.
摘要
儿茶酚在豚鼠中诱发的肌阵挛不会因对脑内5-羟色胺（5-HT）的操作而改变。给予儿茶酚不会改变脑内5-HT或其代谢产物5-羟吲哚乙酸的水平。因此，这种形式的肌阵挛与人类发生的对5-HT敏感的缺氧后动作性肌阵挛无关。
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