对从美国西部山间地区儿科人群中分离出的百日咳博德特氏菌菌株进行红霉素耐药性监测与检测。
Surveillance and detection of erythromycin resistance in Bordetella pertussis isolates recovered from a pediatric population in the Intermountain West region of the United States.
作者信息
Korgenski E K, Daly J A
机构信息
Primary Children's Medical Center, Salt Lake City, Utah 84113, USA.
出版信息
J Clin Microbiol. 1997 Nov;35(11):2989-91. doi: 10.1128/jcm.35.11.2989-2991.1997.
Forty-seven Bordetella pertussis isolates recovered from January 1985 to June 1997 at Primary Children's Medical Center were tested for erythromycin resistance. Agar dilution MICs were determined on Regan-Lowe agar. Forty-six isolates were found to be erythromycin susceptible (all MICs were less than or equal to 0.12 microg/ml). One isolate was found to be erythromycin resistant (MIC, 32 microg/ml). In addition, we compared Etest MIC results and disk diffusion zone diameter measurements, performed on commercially prepared Regan-Lowe agar, to the agar dilution MIC result. Etest MIC and/or disk diffusion testing on commercial Regan-Lowe agar appears to be an adequate method for erythromycin resistance screening of B. pertussis isolates.
对1985年1月至1997年6月期间在 Primary Children's Medical Center 分离出的47株百日咳博德特氏菌进行了红霉素耐药性检测。在Regan-Lowe琼脂上通过琼脂稀释法测定最低抑菌浓度（MIC）。发现46株菌株对红霉素敏感（所有MIC均小于或等于0.12微克/毫升）。发现1株菌株对红霉素耐药（MIC为32微克/毫升）。此外，我们将在商业制备的Regan-Lowe琼脂上进行的Etest MIC结果和纸片扩散法抑菌圈直径测量结果与琼脂稀释法MIC结果进行了比较。在商业Regan-Lowe琼脂上进行Etest MIC和/或纸片扩散试验似乎是一种用于百日咳博德特氏菌分离株红霉素耐药性筛查的合适方法。
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