Sabbah P, Brosset C, Imbert P, Bonardel G, Jeandel P, Briant J F
Department of Infectious and Tropical Diseases, HIA LAVERAN, Marseille Armées, France.
Neuroradiology. 1997 Oct;39(10):708-10. doi: 10.1007/s002340050491.
We report a case of human African trypanosomiasis caused by Trypanosoma brucei rhodesiense. After the febrile period of parasite dissemination, the patient had meningeal involvement but normal CT. MRI showed the appearances of meningitis. After two periods of arsenical treatment, a severe encephalopathy occurred suggesting post-therapeutic reactive encephalitis (PTRE). Nevertheless, T2-weighted MRI showed no oedema, but focal bilateral high signal areas in the white matter. PTRE was excluded and a third course of treatment was undertaken. The lesions progressively disappeared.
我们报告一例由罗德西亚布氏锥虫引起的人类非洲锥虫病病例。在寄生虫播散的发热期过后，患者出现脑膜受累，但CT检查正常。MRI显示出脑膜炎的表现。经过两个疗程的砷剂治疗后，发生了严重脑病，提示治疗后反应性脑病（PTRE）。然而，T2加权MRI未显示水肿，但白质有双侧局灶性高信号区。排除了PTRE并进行了第三个疗程的治疗。病变逐渐消失。
