Durante A, Rovati C, di Belgiojoso G B, Minetti L
Proc Eur Dial Transplant Assoc. 1976;12:189-96.
In 205 cases of GN the glomerular deposits of C3, C1q, C4, and C3A and the serum levels of the same complement components at the time of biopsy were studied. Alterations of serum complement profile were found only in acute GN, membranoproliferative GN and lupus nephritis, while glomerular deposition was observed with a different incidence and intensity in all nephropathies. A strict correlation between the intensity of deposits and the degree of hypocomplementaemia was found only in early acute GN and in active lupus nephritis.
对205例肾小球肾炎（GN）患者，研究了活检时C3、C1q、C4和C3A的肾小球沉积物以及相同补体成分的血清水平。仅在急性GN、膜增生性GN和狼疮性肾炎中发现血清补体谱改变，而在所有肾病中均观察到不同发生率和强度的肾小球沉积。仅在早期急性GN和活动性狼疮性肾炎中发现沉积物强度与补体血症程度之间存在严格相关性。
