眼睑松弛与阻塞性睡眠呼吸暂停（OSA）综合征。
Eyelid hyperlaxity and obstructive sleep apnea (O.S.A.) syndrome.
作者信息
Robert P Y, Adenis J P, Tapie P, Melloni B
机构信息
Service d'Ophtalmologie, C.H.R.U. Duputyren, France.
出版信息
Eur J Ophthalmol. 1997 Jul-Sep;7(3):211-5. doi: 10.1177/112067219700700302.
PURPOSE
An association between the floppy eyelid syndrome and the obstructive sleep apnea syndrome (O.S.A.) has been reported. We studied eyelid tissue elasticity and other ophthalmologic findings in a large number of patients with sleep disorders.
MATERIAL AND METHODS
Sixty-nine patients with sleep disorders were evaluated. Two thirds were found to have O.S.A., and one third was treated at night by nasal continuous positive airway pressure (nasal C.P.A.P.). Slit lamp examination, eyelid measurements and Schirmer test were performed.
RESULTS
Eyelid hyperlaxity was increased in patients with O.S.A. The floppy eyelid syndrome (associated papillary conjunctivitis), however, was rare. Associated corneal lesions were rare, and most patients were asymptomatic. In some cases, ocular irritation was due to air leaks from nasal C.P.A.P. A significant proportion of patients required treatment for primary open angle glaucoma.
CONCLUSIONS
Our study of 69 patients found an association between O.S.A. and eyelid hyperlaxity.
目的
已有报道称睑皮松弛综合征与阻塞性睡眠呼吸暂停综合征（O.S.A.）之间存在关联。我们对大量睡眠障碍患者的眼睑组织弹性及其他眼科检查结果进行了研究。
材料与方法
对69例睡眠障碍患者进行了评估。其中三分之二被发现患有阻塞性睡眠呼吸暂停综合征，三分之一患者夜间接受经鼻持续气道正压通气治疗（经鼻C.P.A.P.）。进行了裂隙灯检查、眼睑测量及泪液分泌试验。
结果
阻塞性睡眠呼吸暂停综合征患者的眼睑松弛度增加。然而，睑皮松弛综合征（伴乳头性结膜炎）较为罕见。相关角膜病变少见，大多数患者无症状。在某些情况下，眼部刺激是由于经鼻持续气道正压通气漏气所致。相当一部分患者需要治疗原发性开角型青光眼。
结论
我们对69例患者的研究发现阻塞性睡眠呼吸暂停综合征与眼睑松弛之间存在关联。
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