用于海马器官型切片培养物电生理监测的微电极阵列
Microelectrode arrays for electrophysiological monitoring of hippocampal organotypic slice cultures.
作者信息
Thiébaud P, de Rooij N F, Koudelka-Hep M, Stoppini L
机构信息
Institute of Microtechnology, University of Neuchâtel, Switzerland.
出版信息
IEEE Trans Biomed Eng. 1997 Nov;44(11):1159-63. doi: 10.1109/10.641344.
A three-dimensional platinum (Pt) microelectrode array embedded on a micromachined silicon (Si) substrate (porosity of 13%, via hole diameter of 40 microns) has been developed. Electrodes are 35-micron wide and 20-microns high, spaced 200 microns apart and arranged in an elliptic geometry. Integrated within a microperfusion chamber, the devices were used for stimulation and recording experiments of hippocampal slice cultures over a period of several days.
一种嵌入微加工硅（Si）衬底（孔隙率为13%，通孔直径为40微米）的三维铂（Pt）微电极阵列已被开发出来。电极宽35微米、高20微米，间距为200微米，并以椭圆形排列。这些器件集成在一个微灌注室中，用于对海马切片培养物进行长达数天的刺激和记录实验。
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